Human Molecular Genetics
Introduction This project report details the characteristics of human protein “MSH6” highlighting its significance, sequence and homologues. Expasy, Blast, OMIM etc are some of the online databases, which have been used to collect data. Out of the several organisms, Xenopus has been selected as model organism for studying the Cancer disease associated with MSH6 protein. […]
What do you believe about xenotransplantation
Introduction The development of the technique of organ transplantation was one of the major medical advances of the twentieth century. Allotransplantation is now a highly successfully way of treating patients for a wide variety of life-threatening medical conditions, but crucially is dependent on an adequate supply of cadaveric human organs. Because of the enormous success […]
Laboratory Report on Succinate Dehydrogenase (SDH)
Introduction: Succinate dehydrogenase or SDH is a vital component in the tricarboxylic acid cycle (TCA) or Krebs cycle (1,2,3). As an important enzyme in the Kreb’s cycle, succinate dehydrogenase oxidizes succinate to fumarate (1,2). Purification of this enzyme is difficult but it has been isolated from organisms such as Bacillus subtilis, E. coli where it […]
Method for measurement of glucose concentrations
Background It is essential that everyone keeps track of the amount of glucose that circulates around the body. In particular, people who suffer from Diabetes Mellitus or have a history of Diabetes in their family have to be more concerned with the amount of glucose in their body. There are two main bodily fluids, namely […]
Critical Evaluation of a Journal Article
Introduction to the Context of the Study Adipose tissue is linked to induction of insulin resistance, with different fat depots having different impact on health. Indeed, the distribution of body fat appears to be more important than the total amount of fat. Abdominal and, in particular, visceral adipose tissue has been strongly associated with the […]
Inborn Errors of Metabolism: Case Study
Introduction The various types, complexity and clinical symptoms of inborn errors of metabolism present a very big challenge to practicing pediatricians. It is imperative for the physician to be aware of the signs and symptoms of these metabolic errors for early diagnosis and management of these disorders (Burton, 1998). Among the various congenital metabolic errors, […]
Myristoylated Alanine-rich C-Kinase Substrate (MARCKS): Its Role in Cell Adhesion and Cell Spreading
Cells are grouped together in order to form into three-dimensional tissues of animals. They are joined together with the purpose of establishing the tissues’ design or architecture. While tissues have distinct properties and organization, their grouping is based on a vital element- cell adhesion. There is a wide array of methods used by the body […]
Clinical Biochemistry Lab Report: Validating a Method of Measuring Glucose Concentrations
Background Diabetes mellitus is a serious and growing health problem worldwide. The disease is caused by a failure of the body to adequately control the concentration of glucose in the blood, which must be kept within narrow limits in order to allow the cells of the body to function properly (Lawal, 2008). In type I […]
Discuss the use of enzymes in pharmaceutical diagnostic testing
Enzymes are of regular use in medicine and pharmaceutical engineering. They have several valuable industrial and medical applications and it is thought that it is through their ability to catalyse reactions and subsequently lowering the energy required for a reaction to occur which makes them of particular use in industry (Smith et al, 1997). Additionally, […]
The New Treatment of Hepatitis C. Illustrate your essay with specific examples.
Abstract: Over the past three decades Hepatitis C has become one the most prevalent causes of liver disease in the world. It now affects over 180 million people worldwide (3% of the population), with over 30,000 new cases being diagnosed in the US alone every year. Though treatments for hepatitis C exist, only 50% of […]
Green Fluorescent Proteins (GFP's) and Fluorescence Resonance Energy Transfer(FRET) Systems. Illustrate your essay with specific examples.
Illustrate your essay with specific examples. Question The following fluorescence excitation and emission patterns (solid and dashed lines respectively) are of the six major classes of GFP mutants and the wild type. The actual GFPs depicted are: a) wild type (Class 1); b) Emerald (Class 2); c) H9-40 (Class 3); d) Topaz (Class 4); e) […]
Current developments in Seasonal Affective Disorder/Depression
Introduction Seasonal affective disorder (SAD) is a mood disorder which is common in temperate climates. It consists of recurrent major depressive episodes mainly during the winter season when the levels of light are reduced. Otherwise known as the winter depression or winter blues, SAD can lead to major clinical depression (Welberg 2007). It is characterised […]
A critical appraisal of the analytical methods for the qualitative and quantitative analysis of amphetamine
Illustrate your essay with specific examples. Introduction Amphetamine and related derivatives are powerful stimulants of the central nervous system and are widely abused to create hallucination and euphoria, and also as doping agents. The psycho-stimulant activity of amphetamine and amphetamine-derived designer drugs depends on the type of enantiomer (5 times higher for S-(+) enantiomes). The […]